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While astrocytes were historically considered to appear morphological changes in response to injury, trauma, aging, and neurodegeneration (Stephenson et al., 1999

Endogenous cysteine is generated primarily through the transsulfuration pathway, which converts methionine to cysteine 20
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Hence, clarifying the mechanism of necroptosis in pathological processes is particularly important for the prevention and treatment of various diseases

The alterations of lactate metabolism in TC aligns with patterns observed across pan-cancer largely
