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Hierarchical testing was terminated early as the MDS-UPDRS Part II did not reach statistical significance, limiting conclusions on subsequent secondary endpoints

An unplanned 3-day gap during a loading phase is equivalent to an extended weekend break

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5-amino-1MQ (5 mg) is a small-molecule compound studied for its role as a selective NNMT (nicotinamide N-methyltransferase) inhibitor in metabolic and cellular energy research
