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The mitochondria oversee the production of energy and protection of cells from oxidative damage

Oxidative stress is a fundamental concept in biology introduced by the first time by Sies (2015)
However, scientific research shows that very high-dose oral B12 (1,000-2,000 mcg) can be effective for some, as about 1% can be absorbed without intrinsic factor

Nova2010, 33, 370-376

Yet the failure should not surprise anyone
