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Hester 2009)

Mechanism of activation of the nrf2-keap1 pathway by fermented chinese herbal medicines via the gut-liver axis to alleviate cadmium-induced hepatotoxicity

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The main results show that allithiamine, purified and verified by techniques such as matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and high-performance liquid chromatographytandem mass spectrometry (HPLC-MS/MS), has significant antioxidant effects, reducing the production of ROS and suppressing the increase in AGEs induced by hyperglycemia