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doi: 10.1002/fsn3.3272, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 95.Mane S, Kumari P, Singh A, Taneja NK, Chopra R
Nuclear localization of IGF-1R was unaltered in GNE knockdown cells while marginal increase in nuclear retention of IGF-1R was observed in V603L GNE mutant cells

Yoo D, Paracatu LC, Xu E, Lin X, Dinauer MC

Physical improvements in body composition largely persist if lifestyle factors remain consistent
And that's assuming perfect refrigeration
