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2020;140:10851088.e6

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Similar content being viewed by others Introduction Mitochondrial diseases (MDs) are a heterogenous group of inborn metabolic diseases caused by defects in the genes encoding mitochondrial proteins that are required for ATP production from oxidation of substrates via the tricarboxylic acid cycle and the oxidative phosphorylation (OXPHOS)

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Consequently, targeting this signaling network holds promise as an innovative therapeutic strategy for this condition

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Allergic reactions are possible but rare, since glutathione is a naturally occurring substance in the body

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Skin hyperesthesia: An unusual side effect reported in some trial participants, this involves increased skin sensitivity or unusual sensations

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