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Often small fiber damage occurs first, including the peripheral thinly myelinated A fibers as well as unmyelinated C nerve fibers, leading to small fiber neuropathy [9]

Glucose can epigenetically Alter the gene expression of neurotrophic factors in the murine brain cells

It's an -MSH (melanocyte-stimulating hormone) fragment that reduces inflammatory cytokine release

doi:10.1016/j.urology.2021.04.019

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