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Dual luciferase assays were performed for relative luciferase activity in cell groups co-transfected with the pmiRGLO plasmids containing wild type (wt) or mutant type (mt) of MALAT1 (MALAT1-wt, MALAT1-mt), siRNA targeting MALAT1(si-MALAT1) miR-155-5p inhibitor or their control was transfected into KGN cells using Lipofectamine 2000

doi: 10.1093/brain/awy182 149 HuJ.DuanH.ZouJ.DingW.WeiZ.PengQ.et al

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Treatment duration ranged from 4 weeks to 6 months (median 12 weeks) (Table 2)

Copper peptides for pigmentation can be used alongside other treatments, such as vitamin C or gentle exfoliants
