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d , Distribution in gWAT adipocyte size after 12 weeks of HFD feeding (n = 5)

Preclinical research evidence Animal Experiments Obese mouse model: After subcutaneous injection of AOD 9604 (250 g/kg) daily for 8 weeks, the body weight of obese mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue decreased significantly

In vivo studies using xenograft models confirmed such findings (Ren et al

analyzed multi-omics datasets to uncover the role of -alanine metabolism in cellular inflammation in lipopolysaccharide (LPS)-stimulated RAW264.7 cells [163]

A study induced lung cancer using the carcinogen benzo [a]pyrene (BPa), and findings indicated that oral administration of methanolic soursop leaf extract exhibited protective and anticancer properties