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In addition, low IGF-1 subjects in a study were found to possess up-regulated fatty acid metabolism along with down-regulated GLUT-1 gene (in charge of glucose uptake in erythrocytes, brain endothelial cells, eye, peripheral nerve and also responsible for materno-placental glucose transfer) [210]

131A , 1117 (2004) Tafti, M

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3 Mechanisms of ferroptosis regulation There are at least three major regulatory mechanisms that play important roles in the ferroptosis process-the antioxidant regulator NRF2, the transsulfuration pathway, and mechanistic target of the rapamycin (mTOR) (84)

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