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Many people with low B12 feel fatigued and sluggish
The synthesis of the neurotransmitters, such as dopamine, norepinephrine, histamine, and taurine, is B6-dependent (Kennedy, 2016

Glucagon-like peptide 1 as a regulator of food intake and body weight: therapeutic perspectives

While we and others have published a number of papers using GHS-R global knockout mice 13, 14 , the neuron-specific roles of GHS-R and the specific site of actions of GHS-R in the brain remain unaddressed

2021 Apr;106(4):450-455