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This makes them water-soluble and able to be excreted through urine or feces.[ref] Essentially, these two steps need to work in tandem: Phase I : The CYP1B1 or CYP1A1 enzyme breaks down estradiol into the catechol estrogen metabolites

In this form the sulfate of P-APS is reduced to sulfite by the free thiol (reduced) group of Sulfur Assimilation The reduced sulfur is finally transferred from the carrier to O-acetylserine (OAS) forming cysteine : O-acetylserine + H2S (or carrier-S-S-) cysteine + acetate The OAS is formed from serine and acetyl-CoA: serine + acetyl-CoA O-acetylserine + CoA This whole process is illustrated as follows: This is summarized in Fig

Which is a kind of fascinating process

It regulates the expression of various genes involved in antioxidant response, detoxification, and cellular metabolism

Le glutathion est un compos naturellement prsent dans lorganisme, au cur de nombreux processus biologiques