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Consistently, in this study, we observed reduced mRNA levels of antioxidant defense such as sod and nrf2 , along with elevated mRNA levels of keap1 in the liver and muscle of HFD-fed tilapia, indicating the incidence of severe oxidative damage and redox imbalance

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Protective effects of curcumin on diabetic nephropathy via attenuation of kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) expression and alleviation of oxidative stress in rats with type 1 diabetes