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Initially, we found that genes whose expression is upregulated in FH-deficient cells 8 are significantly enriched with oxidative stress genes (hypergeometric P value of 5.505e04, see Methods)

Several important GAGs are found in bone broth, including glucosamine, hyaluronic acid and chondroitin sulfate

doi: 10.1016/j.phytochem.2011.02.012 230

This increases the activity of sirtuins (SIRT1) and PARPs, which are essential for DNA repair and longevity

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