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Nat Rev Immunol 17: 363375, 2017

The operators who have focused on strong infrastructure, clean supply chains, and regulatory preparedness will be best positioned to thrive in the years ahead

Indeed, later studies confirmed that Atx1 is a metallochaperone that transfers Cu(I) to Ccc2 in a direct and reversible manner (Huffman & OHalloran, 2000

doi: 167

This can decrease the synthesis of 5-methyltetrahydrofolate and thus the remethylation of homocysteine
