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Description
There have been isolated reports of reversible hepatic injury following intravenous glutathione administration, emphasizing the need for careful monitoring, especially with repeated or high-dose therapy
It also directly neutralizes hydrogen peroxide and lipid peroxides via glutathione peroxidase, and is required by glutathione S-transferases for detoxification of xenobiotics and reactive metabolites
Consequently, the contribution of xCT to cancer cell growth may be overestimated, whereas the importance of GGTs may be undervalued
Because the transfer of ATP formed in S
2003;285:H2309H2315
