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Therapeutic administration NHPN-1010, an antioxidant compound consisting of HPN-07 and NAC, was prepared in a saline solution that was sterilely-filtered to achieve a final concentration of 60 mg/mL for each component
The progression of AD is associated with BBB dysfunction, even at an early stage (216, 217)
Many downstream target genes of NRF2, such as HO1, SLC7A11, FTH/L, and FPN, are related to the regulation of ferroptosis, suggesting NRF2 is a key negative regulator of ferroptosis [92]
Paolisso 1990)
