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Pathological studies in degenerating neurons have demonstrated that S-nitrosylation of Drp1 specifically mediates aberrant mitochondrial recruitment, thereby triggering cascade activation of PINK1/PARKIN pathway-mediated mitophagy (Li et al., 2019)
Individuals with chronic thromboembolic pulmonary hypertension exhibit differential methylation of multiple probes in pulmonary artery smooth muscle cells (PASMCs), which may be associated with PASMC remodeling
10.1128/msystems.00532-23 24 Janczewski
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