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De novo lipogenesis in human fat and liver is linked to ChREBP- and metabolic health
What it is The Val66Met polymorphism involves a single nucleotide change in the BDNF gene that substitutes valine (Val) for methionine (Met) at position 66 of the proBDNF protein
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Primary cardiomyocyte and immortalized cell line models provide validated systems for mechanistic investigation, revealing concentration-dependent effects on focal adhesion assembly and actin polymerization dynamics
