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Tuo QZ, Liu Y, Xiang Z, Yan HF, Zou T, Shu Y, Ding XL, Zou JJ, Xu S, Tang F, Gong YQ, Li XL, Guo YJ, Zheng ZY, Deng AP, Yang ZZ, Li WJ, Zhang ST, Ayton S, Bush AI, Xu H, Dai L, Dong B, Lei P (2022) Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion

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In addition, cellular cysteine is also available through the transsulfuration (TSS) pathway from the sulfur-containing amino acid methionine

On the other hand, mice lacking IGFBP3, -4, or -5 developed normally and only IGFBP4 deficient mice showed a modest (8590% compared to wild type) growth retardation [108], suggesting that other IGFBPs compensate for the loss of IGFBP5