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It suppresses Th17 cell responses, inhibits dendritic cell maturation, downregulates NADPH oxidase, and enhances glutathione antioxidant pathways to reduce reactive oxygen species and mitochondrial damage (10)

In this metabolic pathway, G6PD supplies reducing energy to red blood cells (RBCs) through NADPH and glutathione (GSSG), which can protect RBCs from oxidative stress

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Bel S, Pendse M, Wang Y, Li Y, Ruhn K, Hassell B, Leal T, Winter S, Xavier R, Hooper L (2017) Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine