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Self-DNA from dying infected endothelial cells that have been engulfed by macrophages can activate TLR9 in these cells to trigger NF-B-controlled inflammatory signalling

Broglio F, Koetsveld Pv P, Benso A, Gottero C, Prodam F, Papotti M, Muccioli G, Gauna C, Hofland L, Deghenghi R, Arvat E, Van Der Lely AJ, Ghigo E
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Third, FAD is the cofactor for NQO1, a Phase II enzyme with a specific job: neutralizing reactive estrogen quinones
