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This is achieved when the ER Ca 2+ -channel, the ryanodine receptor (RyR), is activated by the oxidation of its thiol (-SH) sites (Denniss et al

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co-cultured static IPS-1 cells (an immortem PSC cell line) with two different macrophage cell lines RAW264.7 and BMDM-WT and found that when static IPS-1 cells were co-cultured with RAW264.7 macrophage derived cell lines, IPS-1 is activated