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Once mixed with a diluent (like bacteriostatic water), the clock starts ticking
Cytotoxicity assays of RH-PLGA/chitosan nanoparticles using peripheral blood mononuclear cells and Raw 264.7 macrophages showed IC50 values of 1414 g/mL and 19.3 g/mL, respectively
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Moreover, cytosolic mitochondrial DNA elevation induced by reduced NRF2 signaling in PERK-deficient MDSCs led to STING-dependent production of anti-tumor Type-I Interferon
