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On the basis of the turnover frequency calculations, the catalytic cycle of tellurosubtilisin is faster than that of selenosubtilisin, because of the lower span energy
One of the possibilities is the first enzyme involved in proline metabolism, proline oxidase, as it was already speculated in the previous report (Obayashi et al
Yan N, Xu Z, Qu C, Zhang J
Several research studies have shown that oxidative stress is involved in the misfolding and accumulation of mutant huntingtin protein, which induces proteotoxicity and impairs oxidative metabolism, leading to neuronal damage and death 39 , 40
R.PatelR.KirschD
