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Kope et al., 2023)
This method was originally developed by Dawson et al

The result remained consistent (MR-PRESSO, p = 0.021) (Figure 5) after excluding 1 outlier SNP (rs4588066)

Based on the mean cluster size and intra-cluster correlation coefficient, we adjusted the results from trials with the unit of analysis errors (Higgins et al., 2021)

SCFAs, including acetate, propionate, and butyrate, are essential metabolites for sustaining intestinal homeostasis (26)
