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SIRT1 contributes to the repair of intestinal barrier function by upregulating tight junction proteins, such as zonula occludens-1, through deacetylation of histone H3K9 and the transcription factor FOXO1

doi: 10.3389/fphar.2015.00273 328

They metabolize through different hepatic pathways

The Journal Of Immunology 2001, 166: 747-753

doi:10.1089/acm.2017.0183 [41] Capriello S, Stramazzo I, Bagaglini MF, Brusca N, Virili C, Centanni M
