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The authors research whether TB-500 may tone down this signaling and suggest that the peptide may increase the level of miR-146a, a small regulatory RNA molecule whose role may be to act as an internal brake on inflammatory signaling pathways

Ketamine (Ketalar) is a drug with wide ranging effects on the central nervous system due to its inhibition of glutamate receptors, known as N-methyl-D-aspartate (NMDA) receptors, in the brain

Chem Rev 121:1165311698 Mader JS, Hoskin DW (2006) Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment