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We highlight recent progress in the discovery of selective inhibitors, dual-target inhibitors, allosteric modulators, covalent inhibitors, proteolysis-targeting chimeras (PROTACs), and protein-protein interaction (PPI) modulators

It is postulated that a cell surface ER is probably linked to a G-protein

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After one insertion, the tip begins to dull and the lubricant coating degrades

In this review, the following representative categories of PSMs were selected, their roles in regulating cellular autophagic activities were summarized, and their mechanisms of action in influencing cellular vital activities through the modulation of autophagy were described