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Description
Mechanism of Action: As illustrated in Figure 2, pralidoxime can regenerate cholinesterase activity that has become inhibited by an organophosphate compound when given prior to when chemical aging between the organophosphate & cholinesterase enzyme has occurred

1) and thus is less available to react with NAC (Scheme6, eq

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co-loaded -lipoic acid and curcumin into chitosan nanoparticles to improve the limited solubility and bioavailability of both drugs

Formulations of nicardipine and two cyclodextrins (hydrophilic HP--CD and hydrophobic triacetyl--cyclodextrin) in different mixing ratios were obtained in order to achieve an initial fast release followed by a prolonged release
