lglutamine glutathione and glutamine analogues that inhibit GGT. Shown are the Biochemical relationship between glutamic acid,

Neurodegenerative Diseases Alzheimer's disease (AD), identified by the buildup of amyloid plaques along with neurofibrillary tangles within the brain, has emerged as the leading cause of dementia and significantly impacts global health

Cyanidin administration (50 mg/kg/day for 8 weeks), both in vivo and in vitro , enhances Sirt6 activity and inhibits the NF-B signaling pathway

ROS-evoked, Ca2+-dependent signalling events, such as cPKC and/or nPKC activation, seem to mediate these harmful effects

On the other hand, the re-remethylation block hypothesis argues the opposite, that decreases in are responsible for increased Hcy, and presumably GSH

This led to the understanding that organodiselenides can be better GPx mimics than the monoselenides