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Hypoxia-activated prodrugs are inactive in their native form, but are activated by reduction under hypoxic conditions such as may occur in solid tumors, and may then kill tumor cells
Choosing between them comes down to medical history, insurance coverage, supply availability, and the side effect profile that fits your life
In contrast, T2DM exhibits more pronounced endothelial dysfunction driven by hypertension and dyslipidemia, which synergize with hyperglycemia to increase vascular permeability (82, 83)
However, asundexian could still become a viable option if its second stroke prevention trial succeeds
Research shows that even when testosterone levels drop, high DHT levels can accumulate in the prostate
