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Inherited ataxias Friedreich's ataxia (FRDA) FRDA is an autosomal recessive neurodegenerative disease caused by mutations in the gene FXN that encodes for the mitochondrial protein, frataxin
Nature 458 , 362366 (2009)

The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model

4 = more than 35 leukocytes/HPF or confluent microabscesses

During the senescence of RBCs and where energy yield is low, PS is externalized to act as an eat me signal to be engulfed by macrophages
