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Though these earlier studies clearly indicate an antioxidant role for BH4, its anti-ferroptotic role in disease remains to be tested
We found that inducing lipid peroxidation with ferroptosis drugs or gpx mutations was sufficient to elevate PS exposure (Fig
Herxing is a commonly used term for a Jarisch-Herxheimer reaction, a temporary worsening of symptoms after treatment begins
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hence all experiments were undertaken at neutral pH
