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People who are pregnant or breastfeeding, those with kidney disease, seizure disorders, or thyroid conditions, and anyone on medications that could interact should avoid it unless a physician specifically approves it

For true skin-tightening results, treatments that go beyond the dermal-epidermal junctionsuch as lasers, injectables, microneedling, or surgeryremain the gold standard. Meet the experts Brendan Camp, MD, a double board-certified dermatologist and dermatopathologist at MDCS Dermatology: Medical Dermatology & Cosmetic Surgery in the tri-state area Angela Casey, MD, a board-certified dermatologist and founder of Bright Girl based in Columbus, Ohio Mona Foad, MD, a board-certified dermatologist and founder of MONA Dermatology in Cincinnati Mona Gohara, MD, a board-certified dermatologist based in Connecticut and an associate clinical professor at Yale University Saami Khalifian, MD, a board-certified dermatologist and founder of SOM Aesthetics in San Diego Purvisha Patel, MD, a board-certified dermatologist and founder of Visha Skin based in Memphis Rachel Westbay, MD, a board-certified dermatologist at Marmur Medical in New York City How we test and review products When Allure tests a product, our editors look at it from every angle in an effort to best serve you

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Improves nitric oxide bioavailability