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They are administered via intramuscular injection, typically on a weekly basis

A conjugate according to claims 1 or 2, wherein the ligand is selected from the group consisting of: glutathione, S-(p-bromobenzyl)glutathione, gamma-(L-gamma- azaglutamyl)-S-(p-bromobenzyl)-L-c ysteinyl g lycin, S-butylglutathione, S- decylglutathione, glutathione reduced ethyl ester, glutathionesulfonic acid, S- hexylglutathione, S-lactoylglutathione, S-methylglutathione, S-(4- nitrobenzyl)glutathione, S-octylglutathione, S-propylglutathione, n-butanoyl gamma- glutamylcysteinylglycine, ethanoyl gamma-glutamylcysteinylglycine, hexanoyl gamma-glutamylcysteinylglycine, octanoyl gamma-glutamylcysteinylglycine, dodecanoyl gamma-glutamylcysteinylglycine, GSH monoisopropyl ester (N-(N-L- glutamyl-L-cysteinyl)glycine 1-isopropyl ester sulfate mono hydrate) and glutathione derivatives of the formula I: wherein Z=CH 2 and Y=CH 2 , or Z=O and Y=C

& Zani, A

10.1016/j.immuni.2016.01.001 69 Larson-CaseyJ