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Moreover, the higher reproducibility of DIA compared to DDA likely comes from the multiple fragments measured over an elution profile, whereas single elution profile quantification is performed in DDA

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Whatever the case, what is clear is that there are strong correlations at the level of evidence (potentially causal relationship), and whether due to it directly or indirectly, its increase is a factor to be taken into account and should not be ignored

GUB014295 is an RA that activates amylin and CTR, thereby being classified as a DACRA [117]