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Methods Animal experiment Male SHR and WKY rats, aged 2, 3, 4, 6, 8, 10, 12 and 16 weeks, were obtained from the Laboratory Animals Research Unit of Universiti Sains Malaysia, Health Campus, Kubang Kerian, Kelantan, Malaysia and housed at room temperature with a 1212 h lightdark cycle (06001800 hours), and with access ad libitum to food and water throughout the experimental period

The overlapping effects on the glutamatergic system of ALC and NAC could help treat COVID-19 psychiatric symptoms and PCS, acting through different mechanisms on the xc-mGluR2 network, with potentially synergistic effects on chronic pain and neuro-astrocyte protection

The hierarchy of corticostriatal information processing that normally permits the prefrontal cortex to regulate reinforcement-seeking behaviours is impaired by chronic drug use

In mouse and human, around 6070% of genes have a CpG island in their promoter region and most of these CpG islands remain unmethylated independently of the transcriptional activity of the gene, in both differentiated and undifferentiated cell types

doi: 10.3389/fmicb.2022.943791 120 Zaga-ClavellinaVGarcia-LopezGFlores-PliegoAMerchant-LariosHVadillo-OrtegaF