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This extended single dose toxicity study is the minimal requirement to perform Phase 0 clinical trials in humans

PCLiS, as the only tissue-based model system, demonstrated very promising results in detecting DNA-strand breaks caused by NDMA, and the absence of genotoxicity for the negative control NPro

Generally, we review the preclinical data files and give our clients feedback and suggestions regarding the safety aspects of the study

Research trials typically used cream-based formulations at this concentration range applied for 812 weeks before significant results were measured

Successfully adding any new active ingredient is all about understanding where it fits, what concentration to aim for, and which other ingredients will be its best friends