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These mean the native peptide therapy, and the myotendinous junction recovery along with the described beneficial effect in the muscle [21,35,36,37] and tendon healing [18,19,20,22], unmistakably attributed all of its effects (i.e., functional, biomechanical, macroscopic, and microscopic effects and exemplified mechanism(s)) to define myotendinous junction healing in practice

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Looking ahead, integrative approaches combining humanized immune models with engrafted human glia, engineered BBB systems and CNS organoids offer promising avenues to capture patient-relevant inflammatory, degenerative and repair processes

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