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Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement

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[DOI] [PubMed] [Google Scholar] 94.Wrotek S., Sobociska J., Kozowski H.M., Pawlikowska M., Jdrzejewski T., Dzialuk A

Grx1 knockout mice show increased cellular protein S -glutathionylation 42 , and Grx2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells 43

Cancer cells harness these redox-sensitive pathways to maintain uncontrolled growth and enhance their proliferative capacity [31, 33]