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In the central nervous system, niacin is known as a key mediator of neuronal development and survival ( Current evidence has shown that a deficit of mitochondrial energy metabolism is involved in the pathogenesis of migraine headaches ( Pantothenic acid Pantothenic acid is involved in the biosynthesis of coenzyme A, cholesterol, fatty acids, and acetylcholine ( Current evidence suggests that pantothenic acid deficiency causes neurological disturbances ( Pyridoxin Vitamin B6 consists of three main forms including pyridoxine, pyridoxamine, and pyridoxal

10.1161/JAHA.115.002767 91 ShahzadK.BockF.DongW.WangH.KopfS.KohliS.et al (2015)

[DOI] [PubMed] [Google Scholar] 62.Di Lorenzo C., Pierelli F., Coppola G., Grieco G.S., Rengo C., Ciccolella M., Magis D., Bolla M., Casali C., Santorelli F.M., et al