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Thus, local homeostatic disorders and any pH alteration directly impair the integrity of the mucosa, which has a functional role in the internal and external adaptable slope (Borgogna et al., 2020

At the mechanistic level, NCs modulate several signaling pathways, such as PI3K/AKT/mTOR, NF-B, MAPK, and Wnt/-catenin pathways

J.,, XXXI :64-72, 2003 Devitt, A., Grauer, J.N., Beiner, J.B., Kwon, B.K., Vaccaro A.R..: SpineLine review

10.1136/gut.21.6.512 103

As a preventative measure before giving medications known to have ototoxic side effects, NACs use was crucial
