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Proc Natl Acad Sci 95:1486314868 Gaber A, Burritt DJ, Hossain MA (2017) Transgenic plants over-expressing glutathione biosynthetic genes and abiotic stress tolerance

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Concurrently, oxidative stress is significantly increased during inflammation, and upregulated NOX1 expression in microglia increases reactive oxygen species (ROS) levels, thereby exacerbating glutamate neurotoxicity and ultimately worsening neuronal damage [300, 301, 309]

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