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Antidepressants (selective serotonin reuptake inhibitors and tricyclic antidepressants) and anxiolytics are often prescribed off-label, but it is unclear whether they treat the tinnitus or the associated symptoms and there is not sufficient evidence of effectiveness in the absence of depression (199, 200)

First, EM studies in early development have suggested that excitatory shaft synapses precede the formation of spine synapses (Fiala et al., 1998

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The enzyme has been cloned from porcine, bovine, and rat tissues (Jakob et al., 1992, Mitta et al., 1992, Perrier et al., 2004, Raphel et al., 1999)