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Gastrointestinal adverse events were the most frequently reported, but were predominantly mild to moderate

789 PCPs are wellsituated to detect dementia because they often have longstanding relationships with patients 790 , 791 and may witness clinical manifestations of cognitive declineboth overt functional and communication changes and subtle signs, such as irregularities in medication or appointment adherence, loss of control of chronic disease, weight loss, or increased emergency department visits or hospitalizations

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