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Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
PUFAs undergo both nonenzymatic and enzymatic transformations
2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis

doi: 10.1186/s12964-024-01914-1 99 ZhaoXYLiSSHeYXYanLJLvFLiangQMet al

Furthermore, MC4R-deficient mice develop severe obesity accompanied by markedly elevated plasma leptin concentrations and leptin resistance, failing to respond to leptins anorectic and cardiovascular effects [58, 59]
