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Description
Two enzymes are involved in synthesis of GSH: -glutamylcysteine ligase (also called -glutamylcysteine synthetase) and gluthathione synthase (Fig
doi: 10.1093/jxb/ert172
10.1161/01.RES.0000251668.39526.c7 259
10.1016/j.intimp.2022.108553 26 FarzanM.FarzanM.ShahraniM.NavabiS
In controlled studies, glutathione supplementation increased peroxisome proliferator-activated receptor- coactivator-1 (PGC-1) protein levels by 25% and mitochondrial DNA biogenesis by 53% in skeletal muscle, indicating enhanced mitochondrial function supporting exercise capacity
