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We discuss findings from post-mortem investigations, clinical presentations, driving under the influence of drugs cases, and drug-facilitated crime, highlighting the compounds most commonly encountered, including bromazolam, etizolam, and desalkylgidazepam, and how patterns have changed over time

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Its tertiary amine structure facilitates penetration across the bloodbrain barrier, enabling central nervous system (CNS) effects via interaction with central muscarinic receptors

Saturable transport varies for each molecule, depending on blood concentration and endothelial cell receptors

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