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Koyama K, Yoshida A, Takeda A, Morozumi K, Fujinami T, Tanaka N

High abdominal pressure at 25, 30, 40, or 50 mmHg was maintained until sacrifice at 60 min (25 mmHg), 30 min (30 mmHg, 40 mmHg), or 15 min (50 mmHg)

Technique and depth are critical factors in achieving optimal results

Subsequently, it activated the phosphorylation of VEGFR2, Akt, and eNOS signal pathway without the need for other known ligands or shear stress
